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杨永兰,陈群玉.药物联合治疗幽门螺杆菌阳性消化性溃疡52例观察[J].同济大学学报(医学版),2001,(6):38-40. [点击复制]
- .Observation of Drug Combination in Treatment of 52 Cases with Peptic Ulcer Positive in Pylorus Helicobacterium(Hp)[J].Journal of Tongji University(Medical Science),2001,(6):38-40. [点击复制]
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药物联合治疗幽门螺杆菌阳性消化性溃疡52例观察 |
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摘要: |
目的:观察奥美拉唑,阿莫西林和甲哨唑联合搭配,疗程和剂量的效果来探索理想治疗幽门螺杆菌(Hp)的方案,方法:Hp阳性的十二指肠溃疡40例,胃溃疡12例随机分成治疗组和对照组,观察记录Hp根除,溃疡愈合,临床症状改善情况及复发率。结果:两组比较,溃疡愈合率治疗组为96%,对照组88.9%,差异无显著性(P>0.05);Hp根除率治疗组为80%,对照组7.4%,差异非常显著(P<0.005),结论:奥美拉唑,阿莫西林和甲哨唑联合14d治疗方案具有药物量小,疗程短,疗效高,副反应小,价格适宜等特点,是较为理想的根除Hp,治愈溃疡,降低溃疡复发率的方案。 |
关键词: 奥美拉唑 幽门 消化性溃疡 |
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修订日期:2001-02-28 |
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Observation of Drug Combination in Treatment of 52 Cases with Peptic Ulcer Positive in Pylorus Helicobacterium(Hp) |
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Abstract: |
Objective To explore a method for treating Hp by observing the curative effects of a combination of omeprazole,amoxicillin and metronidazole in conditions of different proportions,courses and doses.Methods 40.cases with duodenal ulcers and 12 cases with |
Key words: omeprazole,pylorus,peptic ulcer,pylorus helicobacterium(Hp) |
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