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  • 曲申,毕燕龙.黄斑水肿光学相干断层扫描中强反射点的本质和临床意义[J].同济大学学报(医学版),2023,44(2):278-282.    [点击复制]
  • QU Shen,BI Yanlong.Nature and clinical significance of hyperreflective dots in OCT images of macular edema[J].同济大学学报(医学版),2023,44(2):278-282.   [点击复制]
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黄斑水肿光学相干断层扫描中强反射点的本质和临床意义
曲申,毕燕龙
0
(同济大学附属同济医院眼科,上海200065)
摘要:
黄斑水肿是一种以黄斑内液体积聚为特征的眼部疾病,可引起患者视力严重损害。其常继发于视网膜血管疾病、内眼手术后、视网膜色素变性以及炎症。自光学相干断层扫描成像技术自问世以来,凭借高分辨率、非接触、无创及快速的优势广泛地应用于眼科临床,其清晰的视网膜超微结构图像大大提高了对黄斑水肿的检测水平。其中光学相干断层扫描图像中分布于视网膜全层的强反射信号称之为强反射点,其与治疗预后的相关性是近年关注的热点。目前,强反射点的本质来源以及对临床诊疗的启示尚不完全明确,本文就以上问题进行综述。
关键词:  强反射点  黄斑水肿  光学相干断层扫描成像
DOI:10.12289/j.issn.1008-0392.22200
投稿时间:2022-05-13
基金项目:同济大学2019年重点领域学科交叉重大项目(15022150004);同济大学附属同济医院优秀学科后备人才计划(HBRC2007)
Nature and clinical significance of hyperreflective dots in OCT images of macular edema
QU Shen,BI Yanlong
(Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China)
Abstract:
Macular edema is an eye disease characterized by the accumulation of fluid in the macula which can cause severe impairment of vision. It is often secondary to retinal vascular disease, retinal pigment degeneration, inflammation and inner eye surgery. Optical coherence tomography(OCT) has been widely used in clinical ophthalmology with advantages of promptness, non-contact, non-invasiveness and high resolution; its clear retinal ultrastructural images greatly improve the detection level of macular edema. On the OCT images of macular edema, strong reflection signals distributed in the whole layer of the retina can be observed, which are called hyperreflective dots and become the hot spot of research in recent years. However, the nature and clinical implications of hyperreflective dots in macular edema are still unclear, this article reviews the current research advances in this field.
Key words:  hyper reflective dots  macular edema  optical coherence tomography

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