Abstract:Mattresses, pillows, and desks/chairs—key elements of daily human-environment interaction—play a crucial role in biomechanical spinal alignment. However, most commercial furniture products are designed based on average anthropometric data, neglecting individual differences such as height, body shape, and posture preferences, which may result in poor posture and increased risk of musculoskeletal disorders. To address this issue, a multidisciplinary expert panel in orthopedics, rehabilitation, and ergonomics developed this expert consensus. Drawing upon evidence-based research, national and international standards, and local anthropometric datasets, the consensus proposes 13 detailed recommendations, including mattress zoning and firmness customization, pillow height and contour design, ergonomic dimensions of desks and chairs, backrest tilt and support configuration, population-specific fitting strategies, and functional adjustability. Emphasizing the principle of “personalized adjustment,” this consensus aims to guide tailored mattress and furniture configurations for various age groups and spinal health needs, thereby preventing spinal strain and postural disorders, while enhancing comfort and quality of life.