摘要: |
目的 探讨大鼠肠缺血再灌流致肺损伤与氧自由基的关系。方法 成年雄性SD大鼠,随机分为假手术,肠缺血2h,肠缺血2h再灌流1h三组,分别测各组肺毛细血管通透性及血浆和肺组织丙二醛(MDA)含量,过氧化物歧化酶(SOD)活性。结果 肠缺血再灌流组各指标均显著不同于缺血组及假手术组,MDA与肺毛细血管通透性呈正相关关系。结论 肠缺血再灌流时机体MDA含量增加,SOD活力减弱。氧自由基参与了肺损伤的病理过程。 |
关键词: 肠缺血 再灌流 氧自由基 肺损伤 并发症 病理学 |
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The Effects of Oxygen Free Radicals on Lung Injury from Intestinal Ischemia-Reperfusion in Rats |
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Abstract: |
Objective To investigate the relationship between oxygen free radicals and lung injury from intestinal ischemia reperfusion and oxygen free radicals in rats.Methods 24 adult male SD rats were randomly divided into three groups ( n =8),such as sham op |
Key words: intestinal ischemia reperfusion,oxygen free radicals,lung injury,rats |