| 摘要: |
| 目的 研究绝经后妇女脂蛋白(a)[lipoprotein(a),Lp(a)]与骨代谢之间的关系。方法 选取60名绝经后妇 女,可排除影响骨、脂代谢疾病,按照脂蛋白(a)水平[高Lp(a)≥300 mg／L]分成高Lp(a)组(n=40,平均年龄 58．81±10．89岁)和对照组(平均年龄57．33±9．78岁),运用双能X线骨密度仪(dual energy X-ray absortiometry, DEXA)对研究对象腰椎正侧位、股骨进行骨密度测定,运用ELISA法1对血骨钙素(osteocalcin,OT)、尿I型胶原交 联N端肽(cross-linked N-Telopeptide of I collagen,NTX)及肌苷进行检测。结果 高Lp(a)组血骨钙素值偏高(P< 0．05),股骨总骨密度值偏低(P<0．05),Lp(a)与股骨多个部位骨密度负相关。结论 Lp(a)是影响绝经后妇女骨 代谢的一个因素,Lp(a)可能通过影响骨转换而影响股骨骨量。 |
| 关键词: 绝经后 脂蛋白（a） 骨代谢 |
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| 修订日期：2005-06-28 |
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| The Relationships between Lipoprotein(a) and Bone Metabolism in Postmenopausal Women |
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| Abstract: |
| Objective To study the relationships between lipoprotein(a) [Lp(a)] and bone metabolism, in post-menopausal women. Methods 60 Chinese postmenopausal women who had no diseases affecting bone or lipid metabolism were divided into high Lp(a) group[high Lp(a) |
| Key words: postmenopause,lipoprotein(a),bone metabolism, |
