Effect of intracoronary Urapidil administration on preventing no-reflow phenomenon in patients with acute myocardial infarction
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摘要:
目的 对冠脉内注射小剂量乌拉地尔对防治靶血管开通后的无复流现象的作用进行初步研究.方法 我院收治的急性心肌梗死患者并行急诊介入治疗者共48例随机分为为乌拉地尔组(术中加用乌拉地尔冠脉内注射)和对照组(各24例).比较两组患者的术后心肌灌注分级和无复流的发生率.结果 乌拉地尔组术后梗死相关血管血流Blush分级无复流发生率,显著低于对照组(16.67% vs 29.2%)P<0.05.结论 冠脉内注射小剂量乌拉地尔对急性心肌梗死直接介入治疗后无复流现象有一定防治作用.
Abstract:
Objective To investigate the effects of intracoronary bolus of the selective 1-antagonist Urapidil on myocardial perfusion after coronary stenting.Methods Patients from November 2005 to May 2006 who underwent successful coronary reperfusion with primary c