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| 关键词: 药品不良反应：分析：合理用药 |
| DOI：10.3969/j.issn1008-0392.2010.01.023 |
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| A retrospective analysis of 555 cases of drug adverse reactions |
| HUANG Zhi-xun,ZHU De-qiu |
| (Dept. of Pharmaceutical Preparation Section, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China) |
| Abstract: |
| Objective To analyze the characteristics and related factors of adverse drug reaction (ADR) and establish the way of clinical ADR monitoring in future. Methods A total of .5.5.5 ADR reports collected in 2008 were analyzed restrospectively. Results Among the .5.5.5 cases of ADR, the patients at the age of 20 to .59 had the highest incidence. There were 182 kinds of drugs that induced ADR, in which 70.43% (462 cases) were induced by anti-infective drugs, followed by traditional Chinese drugs preparations. Intravenous injection was the common medication inducing ADR (82.17%, 539 cases. ADR were mainly manifested in skin and local lesions, than in alimentary system lesions. Conclusion Clinical departments should pay great attention in monitoring and reporting of ADR in order to reduce and avoid the occurrence of ADR and promote the rational use of drugs. |
| Key words: adverse drug reaction analysis rational drug use |
