| 引用本文： |
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夏冬冬综述,谭军 审校.载荷对椎间盘退变影响的在体动物实验模型研究进展[J].同济大学学报（医学版）,2016,37(1):115-119. [点击复制]
- XIA Dong-dong,TAN Jun.Loading device in animal model for study of mechanism of intervertebral disc degeneration[J].Journal of Tongji University(Medical Science),2016,37(1):115-119. [点击复制]
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| 摘要: |
| 载荷与椎间盘退变之间的关系是研究椎间盘退变机制具的关键点,而设计制造合适的加载装置在动物体内进行加载实验对深入研究和探索载荷与椎间盘退变之间的关系十分重要。本文综述了国内外利用活体实验动物研探索载荷对椎间盘影响的研究,并且评价了各种在体动物模型的特点和优缺点,可以为研究载荷与椎间盘退变关系的研究者在动物模型的选择上提供一定的参考和帮助。 |
| 关键词: 载荷 加载装置 椎间盘退变 动物实验 |
| DOI：10.16118/j.1008-0392.2016.01.025 |
| 通信作者: |
| 投稿时间：2015-03-09 |
| 录用日期： |
| 基金项目:上海市浦东新区学科带头人计划(PWRd-2011-02) |
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| Loading device in animal model for study of mechanism of intervertebral disc degeneration |
| XIA Dong-dong,TAN Jun |
| (Dept. of Orthopedic Surgery, East Hospital, Tongji University, Shanghai 200120, China) |
| Abstract: |
| Compression loading may induce intervertebral disc degeneration (IDD), and the development of a proper loading device in animal model is essential for study of the mechanism of IDD. This article will describe a variety of loading devices used in different animal models in vivo, and discuss their characteristics and advantages. |
| Key words: loading loading device intervertebral disc degeneration animal experiment |
