| 引用本文： |
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包立豪综述,房林 审校.NF-κB信号通路在乳腺癌发生及发展中作用的研究进展[J].同济大学学报（医学版）,2017,38(3):128-132. [点击复制]
- BAO Li-hao,FANG Lin.Research progress on NF-κB signaling pathway in breast cancer[J].Journal of Tongji University(Medical Science),2017,38(3):128-132. [点击复制]
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| 摘要: |
| 乳腺癌是女性中常见的恶性肿瘤之一。乳腺癌的发生、发展、转移及耐药与细胞内的信号通路密切相关,其中NF-κB信号通路尤为重要。深入了解NF-κB信号通路的作用机制,对于研究乳腺癌发病机制和寻找新的治疗靶点至关重要。本文对NF-κB信号通路在乳腺癌发生及发展中的作用进行综述。 |
| 关键词: 乳腺癌 细胞核因子κB 信号通路 |
| DOI：10.16118/j.1008-0392.2017.03.027 |
| 通信作者: |
| 投稿时间：2016-03-20 |
| 录用日期： |
| 基金项目:国家自然科学基金(81272240) |
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| Research progress on NF-κB signaling pathway in breast cancer |
| BAO Li-hao,FANG Lin |
| (Dept. of Breast and Thyroid Surgery, Tenth People's Hospital, Tongji University, Shanghai 200072, China) |
| Abstract: |
| Breast cancer is one of the most common malignant tumors in women. The occurrence, development, metastasis of breast cancer and its drug resistance are closely related to the intracellular signaling pathways, including the NF-κB signaling pathway. Insight into the mechanism of NF-κB signaling pathway is important for understanding the pathogenesis and seeking effective therapeutic targets of breast cancer. This paper reviews the research progress of NF-κB signaling pathway and its role in the development of breast cancer. |
| Key words: breast cancer nuclear factor kappa B signaling pathway |
