自拟“助眠1号方”对亚健康阴虚火旺型失眠的疗效观察

Clinical observation on Sleep-enhancing Decotion Ⅰ in treatment of sub-health insomnia patients with TCM hyperactive fire due to yin deficiency syndrome

关键词:  失眠  亚健康  阴虚火旺型  睡眠质量  生活质量

Key words:  insomnia  sub-health state  hyperactive fire due to yin deficiency syndrome  sleep quality  quality of life

摘要:

目的观察自拟“助眠1号方”治疗亚健康阴虚火旺型失眠的临床效果。方法将60例亚健康阴虚火旺型失眠患者根据随机数字表法分组,观察组和对照组各30例，对照组采取常规治疗，观察组患者给予自拟“助眠1号方”治疗，治疗4周。比较两组患者临床疗效，治疗前后采用匹兹堡睡眠质量指数（Pittsburgh sleep quality index, PSQI）、世界卫生组织生活质量测定量表简表（WHOQOL-BREF）评价两组患者睡眠质量和生活质量。结果两组患者治疗后PSQI评分降低、WHOQOL-BREF评分升高，且观察组PSQI评分低于对照组、WHOQOL-BREF评分高于对照组（均P<0.001）；观察组患者总有效率为83.33%，高于对照组的60.00%（χ2=4.022，P=0.045）。结论自拟“助眠1号方”可改善亚健康阴虚火旺型失眠患者的近期睡眠质量和生活质量，提高临床疗效。

Abstract:

ObjectiveTo observe the efficacy of Sleep-enhancing Decotion I for sub-health insomnia patients with TCM hyperactive fire due to yin deficiency syndrome. MethodsSixty sub-health insomnia patients with hyperactive fire due to yin deficiency syndrome were randomly divided into two groups： the control group(n=30) received routine treatment, and the TCM group(n=30) received Traditional Chinese medicine Sleep-enhancing Decotion I for 4 weeks. The clinical efficacy was compared between two groups. The Pittsburgh Sleep Quality Index(PSQI) and the World Health Organization Quality of Life-BREF(WHOQOL-BREF) were used to evaluate the sleep quality and quality of life before and after treatment. ResultsThe PSQI score decreased and the WHOQOL-BREF score increased after treatment in both groups(P<0.001). The PSQI score in the TCM group was lower than that in the control group, and the WHOQOL-BREF score in the TCM group was higher than that in the control group(P<0.001). The total effective rate of the TCM group was 83.33%, which was higher than that in the control group(60.00%)(χ2=4.022, P=0.045). ConclusionSleep-enhancing Decotion I can improve the sleep quality and quality of life in sub-health insomnia patients with of hyperactive fire due to yin deficiency syndrome.