联动成像内镜诊断早期胃癌的研究进展

Linked color imaging endoscopy for diagnosis of early gastric cancer

关键词:  联动成像  内窥镜检查  早期胃癌  诊断

Key words:  linked color imaging  endoscopy  early gastric cancer  diagnosis

摘要:

联动成像（linked color imaging, LCI）内镜以增强病灶与周围黏膜的颜色对比度为主要特点，在多种消化道疾病的筛查、诊断上显现出特有的优势。胃癌是我国最常见的恶性肿瘤之一，早期诊断能减少外科手术率、明显改善患者预后。但目前早期胃癌（early gastric cancer, EGC）的诊断率较低，使用普通白光内镜容易漏诊。LCI作为新型的图像增强内镜，已被众多研究证实能够有效提高EGC的诊断率，并有助于EGC与炎症、肠上皮化生的鉴别诊断。此外，在幽门螺杆菌根除后胃癌的筛查与风险评估方面，LCI也具有一定的优势。将LCI与其他内镜技术联用可进一步提升诊断EGC的准确率。因此，LCI在EGC的诊断上具有很好的应用前景。本文将对LCI在EGC诊断方面的研究进展进行阐述，探讨现有研究的不足，以期为今后的进一步完善和探索提供一些有益的参考。

Abstract:

Linked color imaging(LCI) endoscopy is a newly developed image—enhanced endoscopy（IEE）, characterized by enhancing the color contrast between the lesions and surrounding mucosa. It has been used in the detection of various digestive diseases, showing decided advantages in diagnosis. Gastric cancer is one of the most common malignant tumors in China, early diagnosis can reduce the surgical operation rate and significantly improve the survival of patients. However, only a minority of gastric cancer cases are diagnosed early. As a novel IEE, LCI has been proven by many studies to effectively improve the diagnosis of early gastric cancer(EGC), also enable the differentiation of EGC from inflammation and intestinal metaplasia. In addition, LCI can identify important risk factors associated with gastric cancer after successful eradication of Helicobacter pylori infection. The combination of LCI and other endoscopic techniques can further improve the diagnosis of EGC. Therefore, LCI is considered to be a useful tool for the diagnosis of EGC. This article aims to introduce the progress of EGC diagnosis with LCI, discuss the deficiencies of existing researches, and to provide useful references for further studies.